The Dynamics of Cerebrovascular Reactivity Shown with Transfer Function Analysis
J Duffin, O Sobczyk, A P Crawley, J Poublanc, D J Mikulis, J A Fisher. Neuroimage. 2015 Jul 1;114:207-16. doi: 10.1016/j.neuroimage.2015.04.029. Epub 2015 Apr 16.
Cerebrovascular reactivity (CVR) is often defined as the increase in cerebral blood flow (CBF) produced by an increase in carbon dioxide (CO2) and may be used clinically to assess the health of the cerebrovasculature. When CBF is estimated using blood oxygen level dependent (BOLD) magnetic resonance imaging, CVR values for each voxel can be displayed using a color scale mapped onto the corresponding anatomical scan.