Magnetic Resonance Imaging–Based Cerebrovascular Reactivity and Hemodynamic Reserve: A Review of Method Optimization and Data Interpretation
Joseph A. Fisher, Lashmi Venkatraghavan and David J. Mikulis. Stroke. 2018;49:2011–2018. doi.org/10.1161/STROKEAHA.118.021012
Physiological Control of Cerebral Blood Flow
Given adequate perfusion pressure and nonlimiting intracranial or venous pressure, cerebral blood flow (CBF) is regulated to match cerebral metabolic rate of oxygen (CMRO2). Variations in perfusion pressure are addressed by adjusting downstream vascular resistance, termed autoregulation.